Pharma-Assist

Books : Pharmaceutical Technology Controlled-Drug-Release Pharmaceutical Formulation_ The Science and Technology of Dosage Forms Ansel's Pharmaceutical Dosage Forms & Drug Delivery System, 9th Edition Ansel’s Pharmaceutical Dosage Forms and Drug Delivery Systems, 10th Edition Aulton's Pharmaceutics The Design and Manufacture of Medicines, 4th Edition Articles : Microencapsulation Microencapsulation Review Granulation Techniques Targetted DDS Gastroretentive DDS Liposomes Niosomes-1 Niosomes-2 Gene Therapy Resealed Erythrocytes Genetic Engineering Monoclonal Antibodies-1 Monoclonal Antibodies-2 Enzyme Immobilization Immobilization of Enzymes

Potassium Sorbate as Preservative

Potassium sorbate as preservative Potassium sorbate is supplied in granular form that shows that it is not the preservative for liquid and semisolid dosage form because granules enhance the flow of dry powder while in liquid and semisolid dosage form, the preservative is dissolved in water or suitable solvent before its addition into product, so in that case there is no need to add additional step of granulation. Potassium sorbate is used as preservative in sachet commonly and may also be used in dry suspension. It’s one advantage over sodium benzoate is that it is stable till pH 6 while sodium benzoate is stable till pH 5. And potassium sorbate is freely soluble in water as sachet powder requires free solubility because sachet is dissolved in water before use, so it is most suitable in sachet. It also produces very fresh feel in the mouth when taken as sachet solution because it is rapid in action and immediately kills microorganisms in mouth. Mechanism of action: Mechan

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