Biopharmaceutics Paper-2019 (July 17,2019)
Q1. Write notes on the following: (a)
Relationship between Clearance with Half-life (b) Drug Transport across the
cell membrane.
Q2. Describe the
following: (a) Phase-II Drug Metabolism Reactions (b) Linear and Non-Linear
Pharmacokinetics
Q3. Explain Two
Compartment Open Model in detail.
Q4. What is
protein binding? Explain various methods for determination and clinical
significance of drug protein binding.
Q5. Write note
on the following: (a) Methods for assessment of bioavailability (b) In-vitro
and in-vivo correlation (IVIVC)
Industrial Pharmacy Paper-2019 (July
22, 2019)
Q1. (a) Discuss principle, construction,
and working of Vertical Fluidized Bed Dryer.
(b) What are the advantages and disadvantages of Freeze Drying?
Q2. (a) What is comminution? Discuss the
importance of comminution.
(b) Discuss basic principle, construction, working, and advantages of
Colloidal Mill.
Q3. Define and
classify Sterile Area. Discuss in detail different preservatives, antioxidants
and stabilizers used in sterile products.
Q4. (a) Classify
mixers; discuss problems and remedies of centrally mounted liquid-liquid
propeller mixer.
(b) Why cone mixers for solids are designed
asymmetrically and operated with in certain speed limits?
Q5. Write notes
on the following:
(a) Thermostatic
Stream Trap (b) Problems in Tableting (c) Meta Filter
Quality Control Management Paper-2019 (July 25, 2019)
Q1. (a) Define weight variation and write a
general procedure and acceptance criteria for testing the weight variation of
tablets (BP)
(b) Discuss in detail problems encountered during alcohol determination.
Also discuss their remedies.
Q2.
(a) Define the terms: Dissolution and Disintegration with reference to
Pharmacopeias.
(b) Write note on Dissolution Test of
Tablets.
Q3. (a) Discuss water attack test in
detail.
(b) Discuss the principles, construction and working of apparatus
required for moisture determination by Karl-Fisher Method.
Q4. (a) Enlist various Sterility Tests.
(b) Write down the procedure and acceptance criteria for Pyrogen Test.
Q5. Write notes on the followings:
(a) Bioassay of
insulin
(b) Assay of
active ingredient
(c) Friability
Test
Clinical Pharmacy-I Paper-2019 (July 30, 2019)
Q1. Define
adverse drug reaction (ADR). Discuss sub-classes, main features, examples, and
management of Type-B ADRs in detail.
Q2. Define
drug-interactions. Discuss drug-interactions involving induction and inhibition
of metabolism.
Q3. Define
clinical trials. Discuss phases of clinical trials in detail.
Q4. Discuss any two of the following: (a) Treatment of peptic ulcer disease (b) Treatment of asthma (c) Documentation of pharmacotherapy plan
Q5. Discuss any two of the following:(a) Case history (b) Clinical drug profile of ciprofloxacin (c) Primary clinical drug literature
Hospital Pharmacy Paper-2019 (August 2,2019)
Q1. Define Hospital Pharmacy. Discuss roles
and responsibilities of hospital pharmacist.
Q2. Define Formulary. Discuss roles of
P&TC.
Q3. Write note on Dispensing to Inpatients.
Q4. Discuss different methods of Inventory
Control in detail.
Q5. Write down Generic Names, Company
Names, Dosage Forms, Strength, and Indication of following products: (a)
Amoxiclav (b) Rocephin (c) Nivaquine P (d) Toradol (e) Zentel
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